Monday, February 24, 2020
Operations Decision Essay Example | Topics and Well Written Essays - 1000 words
Operations Decision - Essay Example The company has got systems and strategies which assist their clients meet their goals and objectives. XYZ Inc. has in the past adopted a partnership approach to ensure that they work closely and optimize customer contact strategies to live their clients satisfied, increased revenue and with advanced competitive advantage. The company has assisted a number of businesses to develop softwareââ¬â¢s that fits their operations and also get them new markets. With the designed outbound solutions the company helps cover full spectrum of the clients products with the mind that there are the voice of the clientsââ¬â¢ products. Evaluation of Performance Through its various products, the company aims ensuring customer satisfaction through well managed reduced costs by optimizing the business process to support clients. XYZ Inc. has also developed mechanisms to help customers adopt those strategies that ensure valuable long term relationship with their clients. All these strategies have hel ped XYZ Inc. to remain on top of the game and high speed expansion to a number of countries across the globe. Environmental scanning involves study and in-depth interpretation of factors such as political, economical, political, social and technological events which impact the performance of a business. The analyses of these factors are very important as they help determine whether the company should remain in operation or not. Some of the political factors which can influence managerââ¬â¢s decision include taxation policy, trade regulations, government stability and unemployment policy. Given that XYZ Inc. operates in many countries the management is always keen about various regulations. The instability in Syria currently influenced the closure of the offices in that country. Economic factors are also very important in influencing managementââ¬â¢s decision. Some of these are inflation rate, recession and customer liquidation. These factors usually influence the way performan ce as it dictates the companyââ¬â¢s sales. Socio-cultural factors that influence the managementââ¬â¢s decision include age distribution, religion, education levels, life expectancies, population, and income level. The social factors are important as it dictates the purchasing power amongst the clients. When the socio-cultural factors are healthy and favorable in an economy then the power of the targeted clients to buy will be higher. Technology is very important given that XYZ Inc. deals a lot in technological related services. It usually dictates whether the company is in a position to meet the clientââ¬â¢s needs. Some of the technological factors include technological changes, improved distribution channels, improved communication skills. Finally the legal and environmental factors which can also be important to the management include; health and safety law, product safety law, advertising regulations law and the labor laws. All these factors are very important in influen cing the managementââ¬â¢s decisions on either to shut or remain in operation. Total Variable Cost = (Number of Employees X Employees Daily Wage) + Other Variable Costs = (100 X 70) + $2000= $9000 Total Cost = Total Variable Costà +Total Fixed Cost = $ 9,000+ Fixed Cost Worker Productivity = Units of Output per Day / Number of Employees 6,000 units in 20 days= 6,000/20=300 per day 300/100= 3 Total Profit/Loss = Total Revenue ââ¬â
Saturday, February 8, 2020
Migration from Dominican Republic to Puerto Rico in the 80's Essay
Migration from Dominican Republic to Puerto Rico in the 80's - Essay Example The journey of the Dominican Republic was not an easy one but the fact remains that they were able to reach their destination using some boats by the name ââ¬Å"Yolasâ⬠. This essay aims to discuss the Dominican Republics migration to Puerto Rico in the 80ââ¬â¢s. (Ferguson and James) To start with, history has it that there is a close link between Dominican Republic and the Puerto Rico since the pre-Columbian times. This happened when the Arawak people who originated from the Amazon basin of South America came and settled in both territories. The fifteenth and the sixteenth century mark the starting point of the problems in the Dominican Republic when Spain conquered Dominican Republic as well as the Puerto Rico. Spain remained in control until the 19th century and during this time there was a gradual constant flow of people in both directions. The bureaucrats, soldiers, clerics, professionals, students, artisans and slaves were flowing to both directions. Precisely, there we re many exiles that moved from the Hispaniola Island of Puerto Rico in 19th century; this was due to political upheavals. (Falcon and Douglas) The political upheavals comprises of Spain cession of the Island to France, Haitian occupation of Santo Domingo and the Haitian Revolution of the 1804ââ¬â¢s. ... a result of development swift when the Dominican sugar industry moved to the eastern province of San Pedro de Macoris, La Romana and Puerto Plata which attracted so many interested workers form the Caribbean island as well as Puerto Rico. (Bulmer) From this time the historians continued to document the growing number of the people from Puerto Rico in the Dominican Republic and especially in the 20th century. For instance the census done in Dominican showed that there were six thousand and d sixty nine Puerto Ricans living in the Dominican Republic. The religious affinities, linguistic and cultural likeness made the Dominicans and the Puerto Ricans to intermarry which made their second generation not to term themselves as the Puerto Rican but Dominican. However, the period between 1930 and the 1960 had a very minute number of Puerto Ricans migrating to the Dominican Republic and very few Dominicans migrated to Puerto Rico. In 1940 there was a drastic stop of Puerto Rican to the Domini can Republic. Similarly, there was a strict control coming from the Trujillo regime which made it very hard for the Dominicans to travel and only professionals, entrepreneurs and political exiles were able to move and settle in Puerto Rico. Nevertheless, after the death of Trujillo in 1961, there was a large-scale migration from the Dominican Republic to the Puerto Rico. Research shows that there was a dramatic growth of the Dominican population in Puerto Rico. (Moya and pons) There were two major factors that contributed to the migration of the Dominican Republic especially in the 80s. These comprises of political and economic factors. Firstly, the political factors largely contributed to the Dominicans migration. (Ferguson and James) For example, the earliest migrates were linked to the
Wednesday, January 29, 2020
Puritan Ideals of Work and Play in Our World Today Essay Example for Free
Puritan Ideals of Work and Play in Our World Today Essay When Columbus landed in the New World in 1492, he changed the world forever. When the Puritans landed in the same New World, they changed the tides of Americaââ¬â¢s future everlastingly as well. They brought with them many ideas that are still being used today. The Puritan work ethic was a huge portion of the beliefs carried by the community; it was the idea that all members should strive to do as much as they could for the community, and all should work to gain Godââ¬â¢s favor. The Puritansââ¬â¢ idea of duty before self-fulfillment was another evident notion every Puritan held. They believed that everyone should do their obligations first and foremost before anything else. The life of a puritan was full of hard work which was done willingly to gain the favor of God and of the community, and contained the concept of fulfilling each personââ¬â¢s individual responsibilities and then only partaking in activities which where self-fulfilling; in our modern society we volunteer and each member of the family is given duties to complete, similarly to the jobs the Puritans held 100ââ¬â¢s of years ago. In the Puritan world everything revolved around God. He was the cornerstone for every action they took. For them, one way to get redemption from the sins that they had committed was to work and toil for God and the people around them. In the Puritan era people helped one another, not for the chance to gain a reward, but a chance to gain favor amongst themselves, strangers and God. As William Bradford states, ââ¬Å"But when he grew weak, they had compassion on him and helped him,â⬠this refers to the time when the new colonists helped the sick sailors who had brought them there (Bradford 21). They did this just for the sake of helping others and in doing so gained more of Godââ¬â¢s favor. This work ethic inspired the generations of people who followed, and created the standards for American work ethic, which are still being used today. In modern day America, people volunteer at a variety of places to help the poor, needy or injured. My parents when they had just got married spent quite a while at an orphanage in India to help the poor kids there, and I actively volunteer at Mercy Medical to help the sick and injured. Neither my parents nor I had to do so, but it gave us a sense that we were benefiting our communities. Like us, many people in America and the world help others, making the world a better place with every helpful hand. Just as the puritans strived to do work, they also strived to do work which was necessary, even if they did not relish it. For instance when given the choice between trimming tree to make it look better, or helping the neighbor sow his crops, most Puritanââ¬â¢s would choose the later. They had the notion to do your duty first, and all else came afterwards. The Puritanââ¬â¢s believed that the woman of the household should be a good mother and wife first and all else came second. In the same household a man should be a good husband for his wife and a supportive father of his children. In the community, there is not one person who does not have some sort of duty. In Anne Bradstreetââ¬â¢s poem To My Dear and Loving Husband, she describes her love for her husband as his wife, ââ¬Å"I prize thy love more than mines of gold or all the riches the East doth hold (Bradstreet 35). Bradstreet made it quite clear that she was a wife before anything else, being a poet came afterwards. Many of her other poems are about family and hers sense of duty toward them. Puritanââ¬â¢s strove to make their childrenââ¬â¢s lives better, and by being responsible they entailed their kid to do so as well. In modern day America, every member of the household has a specific task that they must do. An example of this is my family, where my parents both maintain their jobs, while tending to the household chores of cooking, cleaning, etc. while my brother and I both do our jobs of doing well in school, while helping our parents where we can. Whether Puritan or modern day American, or Indian in my case, the idea is the same, everyone has tasks they need to do to maintain a functioning household. The Puritan work ethic simply entails that, only after all the work that is needed to be finished is done, should a person partake in other activities or chores. In the Puritan lifestyle family was important; to maintain a good family all the members of it needed to be diligent of their du ties. When someone volunteers in todayââ¬â¢s world they are doing more work to make their society better, when the Puritans did extra hard work they tried to make their community better, and to have a better standing with God. The Puritanââ¬â¢s also did their duty to the best of their ability, and each member of the family functioned together to get their work finished. Both the Puritans and Modern day Americans were partook in hard work and were consistent with their duties to improve their community, and make it a better place for all to live in. All we have to do is maintain these standards in the future, do you think we can?
Tuesday, January 21, 2020
Effects of Catalase Over-expression on Aging :: Biology Age
Introduction What exactly causes the infirmities of old age? According to the free-radical theory of aging, oxidative damage caused by ROS (reactive oxygen species) is the main culprit. This paper focuses on a study that partly supports this theory by showing that murine life span can be extended by an overexpression of human catalase in mitochondria. The specific paper that this is based on is Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria by Samuel E. Schriner et al. Another paper that was used in the construction of this paper is The Anti-Aging Sweepstakes: Catalase Runs for the ROSes by Richard A. Miller. These scientific papers are summaries of the experiments carried out by Schriner and his group dealing with the topic of catalase-overexpression and its effect on murine lifespan. However, it is important to remember that this is a topic still under much debate. Though these experiments do not provide us with a definat cureall for aging, it is believed by many that the data aquired from them point us to one of the major culprits of aging and age related diseases, ROS's. Why the fuss over R.O.S.? Attempts to prolong longevity have been a major endeavor in science and several hypotheses have been proposed about the major causes. Scientists have focused on the role of reactive oxygen species in longevity through investigations using mice models. Reactive oxygen speciesââ¬â¢ role in aging processes is also known as the free radical theory of aging. Scientists have found that reactive oxygen species attack molecules of biological systems and are the main cause for the functional decline of organ systems that lead to eventual death. Various experiments were conducted to investigate the role of reaction oxygen species using transgenic mouse models. Specifically, the purpose of these experiments are to determine if minimizing the level of ROS (reactive oxygen species) in certain organelles in mice have any effect on the overall health and lifespan of the mouse. The hypothesis was tested by amplifying a certain gene in mouse DNA that expresses catalase, an enzyme that breaks down the ROSââ¬â¢s. However, prior to beginning the experiments, transgenic mice are necessary for the experimentation. Development of a Transgenic Mouse A transgenic mouse is a mouse that has had a specific gene, in this case the human catalase gene, inserted into its genome.
Monday, January 13, 2020
Existentialism: Philosophy of Life and Existence Essay
ââ¬Å"Existentialism is an attitude that recognizes the unresolvable confusion of the human world, yet resists the all-too-human temptation to resolve the confusion by grasping toward whatever appears or can be made to appear firm or familiarâ⬠¦The existential attitude begins a disoriented individual facing a confused world that he cannot accept. â⬠(Robert Solomon) Existentialist all share a common concern with what they have coined as the ââ¬Å"Human Condition. â⬠They tend to ask: â⬠¢Why am I here? â⬠¢What does it mean to be human? â⬠¢How should I go about living my life? Existentialism is more of individual rather than social. They, Existentialist need to justify their existence. For them, theyââ¬â¢re having their journey in life to know their purpose based on their own philosophy, according to EDU310 Foundations of Learning. There is no predetermined definition or purpose. We are free to make our own definitions through choices that lead toward self-definition. Students are free agents, responsible for creating their own selves and purpose. Everything learned is a tool toward the realization of oneââ¬â¢s own subjectivity. Standardized testing restricts the interpersonal relationship between teacher and student. Value-laden students are vital, as is authentic assessment. Therefore, Existentialism is a philosophy concerned with human existence, self-discovery, and the search for lifeââ¬â¢s meaning based on free will, experiences, beliefs, laws, and traditions. How does existentialism connect to Axiology and Metaphysics? (Branches of philosophy) In Education, Existentialism is very important, because as an Educator we should know each childââ¬â¢s life, existence and story behind their attitudes and characters, for us to become an effective educator, according to Bethel Jadem. For example, a child has a problem and suddenly changed his/her attitude; we have to know the reason behind it for us to understand him/her. We should know also their philosophy and belief in life so that we could better adjust, know and appreciate their existence as well. To show the connective thread between Axiology and existentialism and metaphysics and existentialism the terms need to first be defined. â⬠¢Axiology is the study of value. It is the branch of philosophy that deals with the nature and types of value such as in ethics and religion. (ââ¬Å"What and why do you value? â⬠) â⬠¢Metaphysics is (ââ¬Å"What is real? â⬠) In connection to axiology, an example of existentialism is: According to EDU 301 Foundations of Learning, studying the ethics of the Christian and Jewish religions is an example of a study in axiology. Therefore, if a child growing up in a Christian home has strong beliefs about God he/she values her beliefs and therefore concludes that here existence is solely because of God. ââ¬Å" There is a purpose for my existence, God will show me the way. â⬠In connection to metaphysics, an example of existentialism is: Since ââ¬Å"thisâ⬠exists, that cannot exist. ââ¬Å"John was walking (this) on water (that). â⬠There is only knowledge of how, beyond what is given, so inferred to make the situation valid with natural cause. As a metaphysical example, if he could walk on water, maybe he had water in his shoes. There is also questions that go beyond what we know. Such as ââ¬Å"is there a ââ¬Å"firstâ⬠cause? â⬠Or is time ââ¬Å"infiniteâ⬠? Since we ourselves can have no observation of such truth, only inference based on given present events, it becomes Metaphysical.
Sunday, January 5, 2020
Azacitidine are DNA Methyltransferase Inhibitors - 641 Words
Azacytidine or 5 AZC Trade Name : Vidaza Introduction: Azacitidine are DNA Methyltransferase inhibitors. Azacitidine being an analog for cytidine gets integrated into the DNA sequence of the DNMT gene, the gene turns dysfunctional, inhibiting the DNA methyltransferase enzymes which normally methylate DNA. Azacitidine is used primarily for the treatment of myelodysplastic syndromes or MDS- a blood disorder which affects the bone marrow leading to a low or ineffective production of blood cells. The cancerous overgrowth of a number of immature cells or blasts and the abnormally developed or dysplastic cells increase, thereby reducing the cell count of normal red blood cells, white blood cells, and platelets. Azacitidine as a chemotherapeutic drug (in low doses) prevents the body from making nucleic acids required for cell growth of the cancerous cells. This stops the growth of cancer cells and leads to cell death. Azacitidine also appears to help restore normal growth and differentiation (cell specialization) in the cells of the bone marrow. This betters the bone marrow production of normal blood cells. Discovery: Azacitidine was first synthesized by Piskala and Sorm in 1964 [Piskala A, Sorm F. (1964). Collect Czech Chem. Commun., 29: 2060-2076]. It was developed as a nucleoside antimetabolite specifically used for the treatment of acute myelogenous leukemia (Cihak, 1974;Sorm et al., 1964). But studies later revealed that this drug inhibited cell mitosis with highShow MoreRelated5-Azacytidine is a Potential Chemotherapeutic Agents for Cancer1430 Words à |à 6 PagesOverview 5-Azacytidine is a chemical analogue of cytidine, a nucleoside present in DNA and RNA with antineoplastic activity. It is sold under the brand name Vidaza. The drug was first synthesized in Czechoslovakia as potential chemotherapeutic agents for cancer. It is an inhibitor of DNA methylation and was approved by the US FDA for the treatment of Myelodysplastic syndromes (MDS) in May 2004. MDS are diseases caused by abnormalities in the blood-forming cells of the bone marrow, which result inRead MoreCancer Therapies And The Lack Of Effectiveness1254 Words à |à 6 Pagestreatments, such as radiation, promote cancer growth. The use of natural products from microorganisms as anticancer therapies was developed in response to the urgent need of initiating more effective treatment options. Histone deacetylases (HBAC) inhibitors have exemplified strong potential, with three compounds approved by the FDA and several other undergoing clinical studies. Du et al. recently conducted a thorough study, describing the potential of a compound known as 1-alaninechlamydocin and itsRead MoreDiet Mediated And Transgenerational Epigenetic Effects1186 Words à |à 5 Pages Martienssen, 2014). One recent study showed that children of obese fathers were at a higher risk of developing obesity themselves. The epigenetic marks of lean and obese men showed similar histone positioning between the two groups but differing DNA methylation patterns, notably in areas of the genome that control satiety. This finding implies that the epigenetic marks of human spermatozoa changed in response to environmental pressure, which in turn p ropagate obesity in future generations (Barrà ¨s
Saturday, December 28, 2019
The United States Of The Declaration Of Independence
On July 4th, 1776 the American Colonists ratified The Declaration of Independence. This Declaration severed their final ties to England and idealized the formation of an equal society, independent of a corrupted centralized government like that of Britain. In order to accomplish this perfect nation, the Americans followed the Declaration with the creation of The Articles of Confederation. The Confederation s purpose was to guide the young republic to a decentralized government that upheld the Republican theory that the common people were in a constant pursuit for the general welfare of all. Nonetheless, with both documents placing the principles of equality and fear of authoritarian power at the center of the nation s identity, distinct social inequalities and issues of greed unveiled themselves. Due to such tyranny, at the end of the eighteenth century America reformed her republic with the institution of a federal constitution. Yet, the emergence of Hamiltonââ¬â¢s Financial Pro gram and the Sedition Act from this reform led the society to segregation and wrought with the unequal distribution of power. Therefore, as the United States of America progressed it did not remain true to its revolutionary ideals of equality and government by the common people to foster a society based on civic virtue. Shortly after the colonists declared their independence in 1776, the perseverance of slavery in the American South revealed the reality that social equality was an unattainable ideal.Show MoreRelatedThe Declaration Of Independence By The United States1106 Words à |à 5 PagesThe setting of the Declaration of Independence was the United States. It was declared on July 4, 1776. After the Boston tea party rebellion the United states wanted their independence. One will describe why the declaration of independence was written. What lead to the cause for writing such a document. The leaders who wrote the declaration. And what the colony was going through for it to lead to the circumstances. One will look at how England was treating the colonies that made them want to be theirRead MoreThe Declaration Of Independence And The United States895 Words à |à 4 Pageswere originally drafted. The U.S. Constitution, the Declaration of Independence, and Thomas Jeffersonââ¬â¢s Letter to the Da nbury Baptist Church are three documents that are still hold relevance in todayââ¬â¢s societal discussions. These three documents hold truths, principals and ideologies that were and are crucial to the continuation and the development of the United States. The very ideas and tribulations that led to the development of the United States are expressed loudly in these three documents. WhileRead MoreThe Declaration Of Independence And The United States897 Words à |à 4 Pages The Declaration of Independence stated the United States should be established as a country, free from British control, the U.S. Constitution is a set of rules for that nation to follow, and Mark Twainââ¬â¢s As Regards Patriotism examines how these two documents affect the mindset of this country. Groupthink, not a word use in 1900, when Twain penned his essay, but it is a good analogy of what he was discussing. Psychology Today says, ââ¬Å"Groupthink occurs when a group values harmony and coherenceR ead MoreThe Declaration Of Independence : The United States1552 Words à |à 7 Pageshappiness. This however was not always the case for the United States. It was once ruled by King George III, and the American people were under the control of the British Parliament. It is what the founding fathers of our country fought for, that made it possible for the United States to be what our country is today. This was only possible by their bravery and the creation of the Declaration of Independence. The Declaration of Independence was a document that was written by Thomas Jefferson, whoRead MoreThe United States Of The Declaration Of Independence1486 Words à |à 6 Pagesthat took the lead on creating one of the first official American documents was the founding fathers. These men signed the Declaration of Independence from England in 1776. They were a group of very strong and independent men who were interested in the future of the country and its ability to stand on its own. Some of the most important men who signed the Declaration of Independence include: George Washington, John Adams, James Madison, Benjamin Franklin, Thomas Jefferson, Alexander Hamilton, and JohnRead MoreThe Declaration Of Independence And The United States1814 Words à |à 8 PagesThe Declaration of Independence is the most imperative and most seasoned report in the United State History. The Declaration was drafted and marked to report our Declaration Of Independence from Great Britain, by saying, â⬠Å" The United Colonies are, and of Right ought to be Free and Independent States; that they are Absolved from all Allegiance to the British Crown, and that all political connection between them and the State of Great Britain is and ought to be totally dissolved; and that as Free andRead MoreThe United States Declaration Of Independence836 Words à |à 4 Pages The United States Declaration of Independence in 1776 expressed that all men are created equal, whose unalienable rights include life, liberty and the pursuit of happiness (The United States National Archives Records Administration, n.d.). Life is the sequence of physical and mental experiences that make up the existence of an individual (Merriam-Webster, 2015). That is to say, the barometer of the wellness and health of a person should include both his biological and psychological/behavioralRead MoreThe Declaration Of Independence And The United States1844 Words à |à 8 Pages The Declaration of Independence is the statement adopted by the Second Continental Congress meeting at Philadelphia, Pennsylvania on July 4, 1776, which announced that the thirteen American colonies, then at war with Great Britain, regarded themselves as thirteen newly independent sovereign states, and no longer under British rule. Instead they formed a new nationââ¬âthe United States of America. John A dams was a leader in pushing for independence, which was unanimously approved on July 2. A committeeRead MoreThe United States And The Declaration Of Independence Essay1150 Words à |à 5 PagesTo continue Jefferson shows these same qualities of independence in the declaration of independence. He wanted the United States to have the freedom to govern itself. According to the author, ââ¬Å"I set out on this ground which I suppose to be self-evident, that the earth belongs in usufruct to the living... We seem not to perceive that, by the law of nature, one generation is to another as one independent nation is to anotherâ⬠¦ The earth belongs always to the living generations,â⬠(Jefferson 5). WhatRead MoreThe United States Declaration Of Independence1802 Words à |à 8 PagesVirginia Convention instructs its Continental Congress delegation to propose a resolution of independence from Great Britain, paving the way for the United States Declaration of Independence. Also, in 1793 Diego Marà n Aguilera flies a glider for about 360 meters, at a height of 5ââ¬â6 meters, during one of the first attempted manned flights. And in 1817 the first private mental health hospital in the United States, the Asylum for the Relief of Persons Deprived of the Use of Their Reason (now Friends Hospital)
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